Background: South Africa accounts for more than a sixth of the global population of people infected with HIV and TB, ranking her highest in HIV/TB co-infection Rubber Disc worldwide.Remote areas often bear the greatest burden of morbidity and mortality, yet there are spatial differences within rural settings.Objectives: The primary aim was to inves
Humans have been using fire for hundreds of millennia, creating an ancestral expansion toward the nocturnal niche.The new adaptive challenges faced at night were recurrent enough to amplify existing psychological variation in our species.Night-time is dangerous and mysterious, so it selects for individuals with higher tendencies for paranoia, risk-
Here we present an alternative technological approach to paper-based microfluidics that, to the best of our knowledge, has not been reported so far.Instead of defining fluid conducting paths by cutting Rubber Disc fluidic structures, or by printing hydrophobic substances on paper, we prepare cellulose/polymer composites that can be printed additive
Coxiella burnetii is the etiological agent of the zoonotic disease Q fever, which is featured by its ability to replicate in acid vacuoles resembling the lysosomal network.One key virulence determinant of C.burnetii is the Dot/Icm system that transfers more than 150 effector proteins into host cells.These effectors function to construct the lysosom